Repeated oxytocin prevents central sensitization by regulating synaptic plasticity via oxytocin receptor in a chronic migraine mouse model

Abstract Background Central sensitization is one of the characters of chronic migraine (CM).Aberrant synaptic plasticity can induce central sensitization.Oxytocin (OT), which is a hypothalamic hormone, plays an important antinociceptive role.However, the antinociceptive effect of OT and the underlying mechanism in CM remains unclear.Therefore, we e

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Sustainability Metrics for Housing and the Thermal Performance Evaluation of a Low-Cost Prototype Made with Poly (Ethylene Terephthalate) Bottles

The scope of this work covers a proposal for the implementation of sustainable, low-cost, environmentally friendly, and affordable housing for low-income people.This paper aims to address the current housing issues, namely that many people lack decent housing and that the built houses are usually of a poorly sustainable nature.The work consists of

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